E-AB-14775
ACLY Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14775
- Zusätzliche Namen:
- ACL,ACLY,ATP citrate (pro-S) lyase,ATP citrate lyase,ATP citrate synthase,ATP-citrate (pro-S-)-lyase,ATP-citrate synthase,ATPCL,ATPcitrate synthase,Acly,CLATP,Citrate cleavage enzyme,OTTHUMP00000164773
- Anwendung:
- WB
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ACLY
- Uniprot:
- P53396
- Synonyme:
- ACL;ATP-citrate (pro-S-)-lyase;ATP-citrate synthase;ATPCL;citrate cleavage enzyme;CLATP
- Weitere Details:
- ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.
- Versandbedingungen:
- Blue Ice