MPG Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-14767
Zusätzliche Namen:: 3 alkyladenine DNA glycosylase,3-alkyladenine DNA glycosylase,3-methyladenine DNA glycosidase,3MG,AAG,ADPG,APNG,Alkyladenine DNA glycosylase,CRA36.1,DNA 3 methyladenine glycosylase,DNA-3-methyladenine glycosylase,MDG,Mid1,Mpg,N methylpurine DNA glyco,anpg
Anwendung:: WB
Konzentration:: 0.7 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human MPG
Uniprot:: P29372
Synonyme:: 3-alkyladenine DNA glycosylase;3-methyladenine DNA glycosidase;3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p;AAG;ADPG;anpg;APNG;CRA36.1;CRA36.1 (3-methyl-adenine DNA glycosylase);DNA-3-methyladenine glycosylase;MDG;Mid1;N-methylpurine-DNA glycosylase;N-methylpurine-DNA glycosylase, MPG;PIG11;PIG16;proliferation-inducing protein 11;proliferation-inducing protein 16
Weitere Details:: Maintenance of DNA sequences is necessary for vertebrates and other life.DNA is under constant stress by a plethora of DNA-damaging agents present in both the environment and within cells.The potentially deleterious effects of DNA lesions in cells are elegantly resolved by sophisticated DNA repair systems, including base excision repair (BER), nucleotide excision repair (NER) and DNA repair methyltransferase (MTase).Methylated bases, such as 3-methyladenine (3MeA) and 7-methylguanine (7MeG) can be formed by agents in the environment and by endogenous cellular processes.Consequently, in the absence of exposure to environmental agents, DNA methylation damage can be incurred on the genomic DNA of normal mammalian cells.DNA N-glycosylases are base excision-repair proteins that locate and cleave damaged bases from DNA as the first step in restoring the sequence.

Versandbedingungen:: Blue Ice