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E-AB-14763

IKZF3 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14763
Zusätzliche Namen:
AIO,Aiolos,IKAROS family zinc finger 3,IKAROS family zinc finger 3 (Aiolos),IKZF 3,IKZF3,Ikaros family zinc finger protein 3,Zinc finger pr,Zinc finger protein Aiolos,Zinc finger protein subfamily 1A 3 (Aiolos),zinc finger DNA binding protein Aiolos
Anwendung:
IHC
Konzentration:
1.6 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human IKZF3
Uniprot:
Q9UKT9
Synonyme:
AIO;AIOLOS;Ikaros family zinc finger protein 3;IMD84;zinc finger DNA binding protein Aiolos;zinc finger protein Aiolos;zinc finger protein, subfamily 1A, 3 (Aiolos);ZNFN1A3
Weitere Details:
This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants.
Versandbedingungen:
Blue Ice