ABI3BP Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-14758
Zusätzliche Namen:: ABI gene family member 3 (NESH) binding protein,ABI gene family member 3 binding protein,ABI gene family member 3-binding protein,ABI3BP,FLJ41743,FLJ41754,Nesh BP,Nesh binding protein,Nesh-binding protein,NeshBP,Target of Nesh SH3,Target of Nesh-SH3,Tarsh
Anwendung:: IHC
Konzentration:: 0.9 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human ABI3BP
Uniprot:: Q7Z7G0
Synonyme:: ABI family, member 3 (NESH) binding protein;ABI gene family member 3-binding protein;ABI gene family, member 3 (NESH) binding protein;nesh-binding protein;NESHBP;target of Nesh-SH3;TARSH
Weitere Details:: A target of NESH-SH3/Abi3bp (TARSH) was originally identified as an SH3 domain-binding molecule of the NESH-SH3/Abi3 protein that is involved in Rac-dependent actin polymerization. In recent studies, TARSH gene expression was dramatically induced in mouse embryonic fibroblasts (MEFs) replicative senescence and suppressed in human lung carcinoma specimens and thyroid carcinomas. However, the molecular mechanism underlying the regulation of TARSH in tumorigenesis remains unclear.