E-AB-14753
ASH2L Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14753
- Zusätzliche Namen:
- ASH 2,ASH2,ASH2 LIKE,ASH2 like protein,ASH2-like protein,ASH2L,ASH2L1>,ASH2L2,Ash2 (absent,Ash2 (absent small or homeotic) like,Ash2l,Bre 2,Bre2,Discs 2-like,Drosophila ASH2-like,Drosophila absent,Set,or homeotic,or homeotic) like (Drosophila),small
- Anwendung:
- IHC
- Konzentration:
- 0.4 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ASH2L
- Uniprot:
- Q9UBL3
- Synonyme:
- ASH2;ash2 (absent, small, or homeotic)-like;ASH2-like protein;ASH2L1;ASH2L2;Bre2;set1/Ash2 histone methyltransferase complex subunit ASH2
- Weitere Details:
- The human ASH2L gene encodes a 628 amino acid protein known as ASH2L1, or isoform 1, which contains a nuclear localization signal and PHD finger motif, suggesting that the gene product functions as a transcription regulator.Alternative splicing results in a shorter isoform 2, designated ASH2L2, which is missing the first 94 amino acid residues found in ASH2L1.Human ASH2L proteins are 60% homologous to Drosophila ash2, which positively regulates expression of certain genes in early development, and contain similar, but not identical, domains, including a zinc finger motif.ASH2L is highly expressed in fetal liver, testis and leukemia cell lines with erythroid and megakaryocytic potential, such as K562, Hel and Dami.
- Versandbedingungen:
- Blue Ice