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E-AB-14744

DRAK2 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14744
Zusätzliche Namen:
DAP kinase related apoptosis inducing protein,DAP kinase related apoptosis inducing protein kinase 2,DAP kinase-related apoptosis-inducing protein kinase 2,DRAK 2,DRAK2,Death associated protein kinase related 2,Serine/threonine,Serine/threonine kinase 17b
Anwendung:
IHC
Konzentration:
0.5 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human STK17B
Uniprot:
O94768
Synonyme:
DAP kinase-related apoptosis-inducing protein kinase 2;death-associated protein kinase-related 2;DRAK2;serine/threonine-protein kinase 17B
Weitere Details:
The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD.The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases.STK17A and STK17B share 59.7% amino acid identity.Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region.Transient transfection of COS-7 cells showed that STK17B localized in nuclei.Phosphorylates myosin light chains.Acts as a positive regulator of apoptosis.
Versandbedingungen:
Blue Ice