E-AB-14732
DCK Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14732
- Zusätzliche Namen:
- DCK,DCK protein,Deoxycytidine kinase,Deoxynucleoside kinase,EC 2.7.1,EC 2.7.1.74,MGC117410,MGC138632,OTTHUMP00000219118,OTTHUMP00000219119,dCK
- Anwendung:
- WB
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DCK
- Uniprot:
- P27707
- Synonyme:
- deoxyadenosine kinase;deoxycytidine kinase;deoxyguanosine kinase;deoxynucleoside kinase
- Weitere Details:
- Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.
- Versandbedingungen:
- Blue Ice