E-AB-14718
GPM6A Polyclonal Antibody

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£106.20
War £118.00
- SKU:
- E-AB-14718
- Zusätzliche Namen:
- GPM6A,M6a,Neuronal membrane glycoprotein M6-a
- Anwendung:
- IHC, WB
- Konzentration:
- 0.4 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human GPM6A
- Uniprot:
- P51674
- Synonyme:
- GPM6;M6A;neuronal membrane glycoprotein M6-a
- Weitere Details:
- Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene.Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells.Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation.GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways.May be involved in neuronal NGF-dependent Ca2+ influx.May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs), enhances internalization and recycling of mu-type opioid receptor.
- Versandbedingungen:
- Blue Ice