E-AB-14693
STK40 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14693
- Zusätzliche Namen:
- 2310004N11Rik,MGC4796,OTTHUMP00000009948,OTTHUMP00000009951,RP11-268J15.4,SHIK,SINK homologous serine/threonine protein kinase,SINK-homologous inhibitory kinase,STK 4,Ser/Thr like kinase,Serine/threonine kinase 40,Serine/threonine protein kinase 40,SgK495
- Anwendung:
- IHC
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human STK40
- Uniprot:
- Q8N2I9
- Synonyme:
- Ser/Thr-like kinase;serine/threonine-protein kinase 40;SgK495;SHIK;SINK-homologous serine/threonine-protein kinase;sugen kinase 495
- Weitere Details:
- STK40 (Serine/threonine-protein kinase 40), also known as Sugen kinase 495, is a 435 amino acid protein kinase that may be a negative regulator of NFK KappaB and p53-mediated gene expression. Localized to both the cytoplasm and the nucleus, STK40 is ubiquitously expressed. STK40 has a central serine/threonine protein kinase domain and is homologous to TRB-3, a protein that regulates activation of MAP kinases and inhibits NFK KappaB-mediated gene transcription. Similarly, overexpression of STK40 inhibits NFK KappaB activation triggered by TNF and also inhibits p53-mediated transcription. There are four named isoforms of STK40 that are produced as a result of alternative splicing.
- Versandbedingungen:
- Blue Ice