E-AB-14627
SETD2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14627
- Zusätzliche Namen:
- EC 2.1.1.43,FLJ16420,FLJ22472,FLJ23184,FLJ45883,HBP231,HIF 1,HIF-1,HIF1,HIP-1,HSPC069,Histone lysine N methyltransferase SETD2,Histone-lysine N-methyltransferase SETD2,Huntingtin intera,Huntingtin interacting protein,Huntingtin interacting protein 1,hSET2
- Anwendung:
- IHC
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human SETD2
- Uniprot:
- Q9BYW2
- Synonyme:
- HBP231;HIF-1;HIP-1;histone-lysine N-methyltransferase SETD2;HSPC069;huntingtin interacting protein 1;huntingtin yeast partner B;Huntingtin-interacting protein 1;huntingtin-interacting protein B;HYPB;KMT3A;LLS;lysine N-methyltransferase 3A;p231HBP;protein-lysine N-methyltransferase SETD2;SET domain-containing protein 2;SET2
- Weitere Details:
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.
- Versandbedingungen:
- Blue Ice