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E-AB-14591

NOL3 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14591
Zusätzliche Namen:
ARC,Apoptosis repressor with CARD,MYC,MYP,Muscle enriched cytoplasmic protein,Muscle-enriched cytoplasmic protein,NOL3,NOP,Nol3,Nop30,Nucleolar protein 3,Nucleolar protein 3 (apoptosis repressor with CARD domain),Nucleolar protein of 30 kDa
Anwendung:
IHC
Konzentration:
0.3 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human NOL3
Uniprot:
O60936
Synonyme:
Apoptosis repressor with CARD;ARC;FCM;muscle-enriched cytoplasmic protein;MYOCL1;MYP;NOP;NOP30;nucleolar protein 3;nucleolar protein 3 (apoptosis repressor with CARD domain);nucleolar protein of 30 kDa
Weitere Details:
This gene encodes an anti-apoptotic protein that has been shown to down-regulate the enzyme activities of caspase 2, caspase 8 and tumor protein p53. Multiple transcript variants encoding different isoforms have been found for this gene. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
Versandbedingungen:
Blue Ice