E-AB-14564
AUP1 Polyclonal Antibody

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£106.20
War £118.00
- SKU:
- E-AB-14564
- Zusätzliche Namen:
- AA589454,AUP 1,AUP1,Ancient ubiquitous protein 1,aup1
- Anwendung:
- IHC, WB
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human AUP1
- Uniprot:
- Q9Y679
- Synonyme:
- ancient ubiquitous protein 1;lipid droplet-regulating VLDL assembly factor AUP1
- Weitere Details:
- This gene encodes a protein that contains a domain with homology to the ancient conserved region of the archain 1 gene and a domain that may be involved in binding ubiquitin-conjugating enzymes. The protein encoded by this gene has been shown to bind to the conserved membrane-proximal sequence of the cytoplasmic tail of integrin alpha(IIb) subunits. These subunits play a crucial role in the integrin alpha(IIb)beta(3) inside-out signalling in platelets and megakaryocytes that leads to platelet aggregation and thrombus formation. This gene overlaps the gene for mitochondrial serine protease 25.
- Versandbedingungen:
- Blue Ice