E-AB-14464
ALKBH2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14464
- Zusätzliche Namen:
- 2OG Fe(II) oxy DC1,9530023G02,ABH 2,ABH2,ALKB2,ALKBH2,ALKBH2 alkB,Alkylated DNA repair protein alkB homolog,Alkylated DNA repair protein alkB homolog 2,Alkylation repair homolog 2,Alpha ketoglutarate dependent dioxygenase ,alkB alkylation repair homolog 2
- Anwendung:
- WB
- Konzentration:
- 0.4 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ALKBH2
- Uniprot:
- Q6NS38
- Synonyme:
- 2OG-Fe(II) oxy DC1;ABH2;alkB, alkylation repair homolog 2;alkylated DNA repair protein alkB homolog 2;alpha-ketoglutarate-dependent dioxygenase alkB homolog 2;DNA oxidative demethylase ALKBH2;oxy DC1
- Weitere Details:
- The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine. Dioxygenase that repairs alkylated DNA and RNA containing 1-methyladenine and 3-methylcytosine by oxidative demethylation. Can also repair alkylated DNA containing 1-ethenoadenine (in vitro). Has strong preference for double-stranded DNA. Has low efficiency with single-stranded substrates. Requires molecular oxygen, alpha-ketoglutarate and iron.
- Versandbedingungen:
- Blue Ice