E-AB-14430
TSLP Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14430
- Zusätzliche Namen:
- TSLP,TSLP protein,Thymic stromal lymphopoietin,Thymic stromal lymphopoietin protein TSLP,Tslp
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human TSLP
- Uniprot:
- Q969D9
- Synonyme:
- thymic stromal lymphopoietin
- Weitere Details:
- This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice