E-AB-14303
PLAUR Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-14303
- Zusätzliche Namen:
- CD 87,CD87,CD87 antigen,MO 3,MO3,Monocyte activation antigen Mo3,PLAUR,Plasminogen activator receptor urokinase,Plasminogen activator urokinase receptor,U PAR,U-PAR,UPA receptor,u plasminogen activator receptor,u-plasminogen activator receptor form 2,uPAR
- Anwendung:
- IHC, WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PLAUR
- Uniprot:
- Q03405
- Synonyme:
- CD87;monocyte activation antigen Mo3;U-PAR;u-plasminogen activator receptor form 2;UPAR;URKR;urokinase plasminogen activator surface receptor;urokinase-type plasminogen activator (uPA) receptor
- Weitere Details:
- This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
- Versandbedingungen:
- Blue Ice