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E-AB-14232

MUTYH Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14232
Zusätzliche Namen:
A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,E. coli,MGC4416,MUTYH,MYH,MutY,MutY (E. coli) homolog,MutY homolog,MutY homolog (E. coli),Mutyh,hMYH,homolog of,rMYH
Anwendung:
WB
Konzentration:
0.4 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human MUTYH
Uniprot:
Q9UIF7
Synonyme:
A/G-specific adenine DNA glycosylase;adenine DNA glycosylase;mutY homolog;mutY-like protein;MYH
Weitere Details:
This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice