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E-AB-14029

CYP1A1 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-14029
Zusätzliche Namen:
AHH,AHRR,Aryl hydrocarbon hydroxylase,CP11,CP1A1,CYP 1,CYP1,CYPIA1,Cytochrome P1 450 dioxin inducible,Cytochrome P1-450,Cytochrome P450 1A1,Cytochrome P450 family 1 subfamily A polypeptide 1,Cytochrome P450 form 6,Cytochrome P450 subfamily I (aroma,cyp1a1
Anwendung:
WB
Konzentration:
0.3 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human CYP1A1
Uniprot:
P04798
Synonyme:
AHH;AHRR;aryl hydrocarbon hydroxylase;CP11;CYP1;CYPIA1;cytochrome P1-450, dioxin-inducible;cytochrome P450 1A1;cytochrome P450 form 6;cytochrome P450-C;cytochrome P450-P1;cytochrome P450, family 1, subfamily A, polypeptide 1;cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1;flavoprotein-linked monooxygenase;hydroperoxy icosatetraenoate dehydratase;P1-450;P450-C;P450DX;xenobiotic monooxygenase
Weitere Details:
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown, however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
Versandbedingungen:
Blue Ice