E-AB-13826
STAT4 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13826
- Zusätzliche Namen:
- SLEB11,STAT4,Signal transducer and activator of transcription 4
- Anwendung:
- IHC
- Konzentration:
- 1.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human STAT4
- Uniprot:
- Q14765
- Synonyme:
- signal transducer and activator of transcription 4;signal transducer and activator of transcription 4 variant 3;SLEB11
- Weitere Details:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein.
- Versandbedingungen:
- Blue Ice