E-AB-13820
CASP10 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13820
- Zusätzliche Namen:
- ALPS2,Apoptotic protease Mch-4,CASP 10,CASP-10,CASP10,CASPA,Caspase 10 apoptosis related cysteine peptidase,Caspase-10 subunit p12,FADD like ICE2,FAS-associated death domain protein interleukin-1B-converting enzyme 2,FL,Fas associated death domain protein
- Anwendung:
- IHC
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CASP10
- Uniprot:
- Q92851
- Synonyme:
- ALPS2;apoptotic protease MCH-4;CASP-10;caspase 10 apoptosis-related cysteine peptidase;caspase 10, apoptosis-related cysteine protease;caspase-10;FADD-like ICE2;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE-2;FLICE2;ICE-like apoptotic protease 4;interleukin-1B-converting enzyme 2;MCH4
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
- Versandbedingungen:
- Blue Ice