E-AB-13815
CASP3 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13815
- Zusätzliche Namen:
- A830040C14Rik,Apopain,CASP-3,CASP3,CC3,CPP-32,CPP32,CPP32B,Casp3a,Caspase 3,Caspase-3 subunit p12,Cysteine p,apoptosis-related cysteine peptidase,apoptosis-related cysteine protease,apoptosis-related cysteine protease a
- Anwendung:
- IHC, WB
- Konzentration:
- 0.5 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CASP3
- Uniprot:
- P42574
- Synonyme:
- apopain;CASP-3;caspase 3, apoptosis-related cysteine peptidase;caspase 3, apoptosis-related cysteine protease;caspase-3;CPP-32;CPP32;CPP32B;cysteine protease CPP32;PARP cleavage protease;procaspase3;protein Yama;SCA-1;SREBP cleavage activity 1
- Weitere Details:
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
- Versandbedingungen:
- Blue Ice