E-AB-13743
LTB Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13743
- Zusätzliche Namen:
- LT beta,LT-beta,Ltb,Lymphotoxin-beta,TNF-C,TNFC,TNFSF3,Tumor necrosis factor C,Tumor necrosis factor ligand superfamily member 3,lymphotoxin beta,p33
- Anwendung:
- IHC
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LTB
- Uniprot:
- Q06643
- Synonyme:
- LT-beta;lymphotoxin beta (TNF superfamily, member 3);lymphotoxin-beta;p33;TNF superfamily member 3;TNF-C;TNFC;TNFSF3;TNLG1C;tumor necrosis factor C;tumor necrosis factor ligand 1C;tumor necrosis factor ligand superfamily member 3
- Weitere Details:
- Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms.
- Versandbedingungen:
- Blue Ice