E-AB-13351
KDM4C Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13351
- Zusätzliche Namen:
- GASC 1 protein,GASC-1 protein,GASC1,Gene amplified in squamous cell carcinoma 1 protein,J,JHDM3C,JMJD2C,JmjC domain containing histone demethylation protein 3C,JmjC domain-containing histone demethylation protein 3C,Jumonji domain containing 2C,bA146B14.1
- Anwendung:
- WB
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human KDM4C
- Uniprot:
- Q9H3R0
- Synonyme:
- [histone H3]-trimethyl-L-lysine(9) demethylase 4C;GASC1;gene amplified in squamous cell carcinoma 1 protein;JHDM3C;JmjC domain-containing histone demethylation protein 3C;JMJD2C;jumonji domain-containing protein 2C;lysine (K)-specific demethylase 4C;lysine-specific demethylase 4C;TDRD14C;tudor domain containing 14C
- Weitere Details:
- This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with one JmjC domain, one JmjN domain, two PHD-type zinc fingers, and two Tudor domains. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form. Chromosomal aberrations and increased transcriptional expression of this gene are associated with esophageal squamous cell carcinoma. Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice