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E-AB-13213

COL18A1 Polyclonal Antibody

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£106.20

War £118.00

SKU:
E-AB-13213
Zusätzliche Namen:
Antiangiogenic agent,COIA1,Col18a1,Collagen alpha 1(XVIII) chain,Collagen type XVIII alpha 1,Endostatin,KNO,KNO1,KS,Multi functional protein MFP
Anwendung:
IHC
Konzentration:
0.6 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human COL18A1
Uniprot:
P39060
Synonyme:
antiangiogenic agent;collagen alpha-1(XVIII) chain;collagen, type XVIII, alpha 1;endostatin;GLCC;KNO;KNO1;KS;multi-functional protein MFP
Weitere Details:
This gene encodes the alpha chain of type XVIII collagen.This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains.The proteolytically produced C-terminal fragment of type XVIII collagen is endostatin, a potent antiangiogenic protein.Mutations in this gene are associated with Knobloch syndrome.The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure.Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice