E-AB-13100
Cav1.2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13100
- Zusätzliche Namen:
- CAC1C,CACH 2,CACH2,CACN 2,CACN2,CACNA1C,CACNL1A1,Calci,Calcium channel,Calcium channel L type alpha 1 polypeptide isoform 1 cardiac muscle,Calcium channel cardic dihydropyridine sensitive alpha 1 subunit,L type,alpha-1 polypeptide,cardiac muscle,isoform 1
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CACNA1C
- Uniprot:
- Q13936
- Synonyme:
- CACH2;CACN2;CACNL1A1;calcium channel, cardic dihydropyridine-sensitive, alpha-1 subunit;Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle;calcium channel, voltage-dependent, L type, alpha 1C subunit;CaV1.2;CCHL1A1;DHPR, alpha-1 subunit;LQT8;TS;TS. LQT8;voltage-dependent L-type Ca2+ channel alpha 1 subunit;voltage-dependent L-type calcium channel subunit alpha-1C;Voltage-gated calcium channel subunit alpha Cav1.2;voltage-gated L-type calcium channel Cav1.2 alpha 1 subunit, splice variant 10*
- Weitere Details:
- This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Alternative splicing results in many transcript variants encoding different proteins. Some of the predicted proteins may not produce functional ion channel subunits.
- Versandbedingungen:
- Blue Ice