E-AB-13059
CCDC88A Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13059
- Zusätzliche Namen:
- AKT iphosphorylation enhancer,APE,Akt phosphorylation enhancer,Ccdc88a,Coiled coil domain containing 88A,Coiled coil domain containing protein 88A,Coiled-coil domain-containing protein 88A,FLJ10392,G alpha interacting vesicle associated protein,G alpha-in
- Anwendung:
- IHC
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human CCDC88A
- Uniprot:
- Q3V6T2
- Synonyme:
- Akt phosphorylation enhancer;AKT-phosphorylation enhancer;APE;Coiled-coil domain-containing protein 88A;g alpha-interacting vesicle-associated protein;Girders of actin filament;girders of actin filaments;girdin;GIV;GRDN;HkRP1;Hook-related protein 1;KIAA1212;PEHO;PEHOL
- Weitere Details:
- This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Versandbedingungen:
- Blue Ice