E-AB-13003
ZFP42 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-13003
- Zusätzliche Namen:
- REX1,REX1 transcription factor,Reduced Expression 1 Protein,Reduced expression protein 1,Rex-1,ZFP42,ZFP42 zinc finger protein,ZNF754,Zfp-42,Zfp42,Zinc finger protein 42 homolog,Zinc finger protein 754,hREX-1
- Anwendung:
- WB
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human ZFP42
- Uniprot:
- Q96MM3
- Synonyme:
- reduced expression protein 1;REX-1;REX1;REX1 transcription factor;zfp-42;zinc finger protein 42 homolog;zinc finger protein 754;ZNF754
- Weitere Details:
- Rex-1 (for reduced expression), also designated zinc finger protein 42 (ZFP42), is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem (ES) and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid (RA), and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
- Versandbedingungen:
- Blue Ice