E-AB-12987
MANF Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-12987
- Zusätzliche Namen:
- ARMET,ARMET protein,ARP,Arginine rich mutated in early stage tumors,Arginine rich protein,Arginine-rich protein,MANF,MGC142148,MGC142150,Manf,Mesencephalic astrocyte derived neurotrophic factor,Mesencephalic astrocyte-derived neurotrophic factor,Protein A
- Anwendung:
- IHC
- Konzentration:
- 0.1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human MANF
- Uniprot:
- P55145
- Synonyme:
- Arginine-rich protein;arginine-rich, mutated in early stage tumors;ARMET;ARP;mesencephalic astrocyte-derived neurotrophic factor;Protein ARMET
- Weitere Details:
- The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors, however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
- Versandbedingungen:
- Blue Ice