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E-AB-12915

TRPM5 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-12915
Zusätzliche Namen:
9430099A16Rik,LTrpC-5,LTrpC5,Long transient receptor potential channel 5,MLSN1 and TRP related gene 1,MLSN1 and TRP related gene 1 protein,MLSN1 and TRP-related,MLSN1- and TRP-related gene 1 protein,MTR1,Novel protein similar to vertebrate transient recep
Anwendung:
IHC, WB
Konzentration:
0.6 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Synthetic peptide of human TRPM5
Uniprot:
Q9NZQ8
Synonyme:
long transient receptor potential channel 5;LTRPC5;MLSN1 and TRP-related;MLSN1- and TRP-related gene 1 protein;MTR1;transient receptor potential cation channel subfamily M member 5
Weitere Details:
This gene encodes a member of the transient receptor potential (TRP) protein family, which is a diverse group of proteins with structural features typical of ion channels. This protein plays an important role in taste transduction, and has characteristics of a calcium-activated, non-selective cation channel that carries Na+, K+, and Cs+ ions equally well, but not Ca(2+) ions. It is activated by lower concentrations of intracellular Ca(2+), and inhibited by higher concentrations. It is also a highly temperature-sensitive, heat activated channel showing a steep increase of inward currents at temperatures between 15 and 35 degrees Celsius. This gene is located within the Beckwith-Wiedemann syndrome critical region-1 on chromosome 11p15.5, and has been shown to be imprinted, with exclusive expression from the paternal allele.
Versandbedingungen:
Blue Ice