E-AB-12872
SLC27A1 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-12872
- Zusätzliche Namen:
- ACSVL5,FATP,FATP 1,FATP1,FLJ00336,Fatty acid transport protein 1,Long chain fatty acid transport protein 1,MGC71751,SLC27A1,Solute carrier family 27 (fatty acid transporter) member 1,Solute carrier family 27 member 1
- Anwendung:
- IHC
- Konzentration:
- 0.1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human SLC27A1
- Uniprot:
- Q6PCB7
- Synonyme:
- ACSVL5;FATP;FATP-1;FATP1;fatty acid transport protein 1;long-chain fatty acid transport protein 1;solute carrier family 27 (fatty acid transporter), member 1;Solute carrier family 27 member 1
- Weitere Details:
- The protein involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. The LFCA import appears to be hormone-regulated in a tissue-specific manner. In adipocytes, but not myocytes, insulin induces a rapid translocation of FATP1 from intracellular compartments to the plasma membrane, paralleled by increased LFCA uptake. Plays a pivotal role in regulating available LFCA substrates from exogenous sources in tissues undergoing high levels of beta-oxidation or triglyceride synthesis. May be involved in regulation of cholesterol metabolism. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids .Highest levels of expression are detected in muscle and adipose tissue small, intermediate levels in small intestine, and barely detectable in liver.
- Versandbedingungen:
- Blue Ice