E-AB-12392
PTGER4 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-12392
- Zusätzliche Namen:
- EP 4,EP4,EP4R,MGC126583,PE2R4,PGE receptor EP4 subtype,PGE2 receptor EP4 subtype,PTGE,PTGER 2,PTGER 4,Prostaglandin E receptor 4,Prostaglandin E receptor 4 subtype EP4,Prostaglandin E2 receptor,Prostaglandin E2 receptor EP4 subtype,Prostanoid EP4 receptor
- Anwendung:
- WB
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human PTGER4
- Uniprot:
- P35408
- Synonyme:
- EP4;EP4R;PGE receptor, EP4 subtype;PGE2 receptor EP4 subtype;prostaglandin E receptor 4 (subtype EP4);prostaglandin E2 receptor EP4 subtype;prostanoid EP4 receptor
- Weitere Details:
- The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses.
- Versandbedingungen:
- Blue Ice