E-AB-12255
LOX Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-12255
- Zusätzliche Namen:
- LYOX,Lysyl oxidase,MGC105112,Protein lysine 6 oxidase,Protein-lysine 6-oxidase,lox
- Anwendung:
- WB
- Konzentration:
- 0.2 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Synthetic peptide of human LOX
- Uniprot:
- P28300
- Synonyme:
- AAT10;Lysyl oxidase;protein-lysine 6-oxidase
- Weitere Details:
- The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice