E-AB-11438
NECTIN4 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-11438
- Zusätzliche Namen:
- DKFZp686K05193,EDSS1,Ig superfamily receptor LNIR,Nectin 4,Nectin-4,PRR4,PVRL4,Processed poliovirus receptor-related protein 4,poliovirus receptor-related 4,pvrl4
- Anwendung:
- IHC, WB
- Konzentration:
- 0.9 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human PVRL4
- Uniprot:
- Q96NY8
- Synonyme:
- EDSS1;Ig superfamily receptor LNIR;LNIR;nectin 4;Nectin cell adhesion molecule 4;nectin-4;poliovirus receptor-related 4;poliovirus receptor-related protein 4;PRR4;PVRL4
- Weitere Details:
- This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
- Versandbedingungen:
- Blue Ice