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E-AB-11311

HSD3B7 Polyclonal Antibody

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£106.20

War £118.00

SKU:
E-AB-11311
Zusätzliche Namen:
3 beta HSD VII,3 beta hydroxy Delta(5) C27 steroid oxidoreductase,3 beta hydroxysteroid dehydrogenase type 7,3 beta hydroxysteroid dehydrogenase type VII,7 alpha diol 3 beta dehydrogenase,AI195443,BB098564,C(27) 3 beta HSD,Cca2,Cholest 5 ene 3 beta,Conflu
Anwendung:
IHC
Konzentration:
0.3 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human HSD3B7
Uniprot:
Q9H2F3
Synonyme:
3 beta-hydroxy-delta 5-C27-steroid oxidoreductase;3 beta-hydroxysteroid dehydrogenase type 7;3 beta-hydroxysteroid dehydrogenase type VII;3-beta-HSD VII;3-beta-hydroxy-Delta(5)-C27 steroid oxidoreductase;c(27) 3-beta-HSD;C(27)-3BETA-HSD;CBAS1;cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase;PFIC4;SDR11E3;short chain dehydrogenase/reductase family 11E, member 3
Weitere Details:
This gene encodes an enzyme which is involved in the initial stages of the synthesis of bile acids from cholesterol and a member of the short-chain dehydrogenase/reductase superfamily. The encoded protein is a membrane-associated endoplasmic reticulum protein which is active against 7-alpha hydrosylated sterol substrates. Mutations in this gene are associated with a congenital bile acid synthesis defect which leads to neonatal cholestasis, a form of progressive liver disease. Multiple transcript variants encoding different isoforms have been found for this gene.
Versandbedingungen:
Blue Ice