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E-AB-11286

GSTA3 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-11286
Zusätzliche Namen:
Glutathione S alkyltransferase A3,Glutathione S aralkyltransferase A3,Glutathione S aryltransferase A3,Glutathione S transfe,Glutathione S transferase A3,Glutathione S transferase A3 3,Glutathione S transferase alpha 3,glutathione S transferase A3 subunit
Anwendung:
IHC, WB
Konzentration:
0.3 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human GSTA3
Uniprot:
Q16772
Synonyme:
glutathione S-alkyltransferase A3;glutathione S-aralkyltransferase A3;glutathione S-aryltransferase A3;glutathione S-transferase A3;glutathione S-transferase A3-3;GST class-alpha member 3;GSTA3-3;GTA3;S-(hydroxyalkyl)glutathione lyase A3
Weitere Details:
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families.These enzymes are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds.At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta.This gene encodes a glutathione S-tranferase belonging to the alpha class genes that are located in a cluster mapped to chromosome 6.Genes of the alpha class are highly related and encode enzymes with glutathione peroxidase activity.However, during evolution, this alpha class gene diverged accumulating mutations in the active site that resulted in differences in substrate specificity and catalytic activity.
Versandbedingungen:
Blue Ice