E-AB-11252
GADD45B Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-11252
- Zusätzliche Namen:
- GA45B,GADD45 Beta,GADD45BETA,Gadd45b,Growth arres,Growth arrest and DNA damage inducible 45 beta,Growth arrest and DNA damage inducible beta,Growth arrest and DNA damage-inducible gene GADD45,Growth arrest and DNA damage-inducible protein GADD45 beta,beta
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human GADD45B
- Uniprot:
- O75293
- Synonyme:
- GADD45BETA;growth arrest and DNA damage-inducible protein GADD45 beta;MYD118;myeloid differentiation primary response protein MyD118;negative growth regulatory protein MyD118
- Weitere Details:
- This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth.
- Versandbedingungen:
- Blue Ice