GAB2 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-11250
Zusätzliche Namen:: GAB 2,GAB2,GRB 2 associated binding protein 2,GRB2 associated binder 2 pp100,GRB2 associated binding protein 2,GRB2-associated binder 2,GRB2-associated-binding protein 2,Gab2,Grb 2 associated binder 2,Grb2 associated binder 2,Growth factor receptor bound
Anwendung:: IHC, WB
Konzentration:: 0.3 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human GAB2
Uniprot:: Q9UQC2
Synonyme:: Grb2-associated binder 2;GRB2-associated-binding protein 2;growth factor receptor bound protein 2-associated protein 2;pp100
Weitere Details:: This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.