E-AB-11144
DCTN3 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-11144
- Zusätzliche Namen:
- DCNT22,DCTN 22,DCTN22,DCTN3,Dctn3,Dynactin complex subunit 22 kDa subunit,Dynactin subunit 3,dynactin 3,dynactin 3 (p22),dynactin 3 isoform 1,dynactin light chain,p22
- Anwendung:
- IHC
- Konzentration:
- 0.6 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human DCTN3
- Uniprot:
- O75935
- Synonyme:
- DCTN-22;DCTN22;dynactin 3 (p22);dynactin complex subunit 22 kDa subunit;dynactin light chain;dynactin subunit 3
- Weitere Details:
- This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD.Dynactin binds to both microtubules and cytoplasmic dynein.It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis.This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex.It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin.Alternative splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice