E-AB-10955
CERK Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-10955
- Zusätzliche Namen:
- Acylsphingosine kinase,CERK1,Ceramide kinase,Cerk,KIAA1646,LK4,Lipid kinase 4,Lipid kinase LK4,dA59H18.2,dA59H18.3,hCERK
- Anwendung:
- IHC
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human CERK
- Uniprot:
- Q8TCT0
- Synonyme:
- acylsphingosine kinase;ceramide kinase;dA59H18.2;dA59H18.3;hCERK;lipid kinase 4;lipid kinase LK4;LK4
- Weitere Details:
- CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides.
- Versandbedingungen:
- Blue Ice