PIM2 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-10916
Zusätzliche Namen:: OTTHUMP00000025825,PIM2,PIM2 Oncogene,Pim 2 oncogene,Pim 2h,Pim-2h,Pim2h,Proto Oncogene PIM2,Proto-oncogene Pim-2 (serine threonine kinase),Serine/threonine kinase PIM2,Serine/threonine-protein kinase Pim-2
Anwendung:: IHC
Konzentration:: 0.3 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human PIM2
Uniprot:: Q9P1W9
Synonyme:: pim-2 oncogene;pim-2h;proto-oncogene Pim-2 (serine threonine kinase);serine/threonine-protein kinase pim-2
Weitere Details:: This gene encodes a protooncogene that acts as a serine/threonine protein kinase. Studies determined the encoded protein functions to prevent apoptosis and to promote cell survival. Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Exerts its oncogenic activity through: the regulation of MYC transcriptional activity, the regulation of cell cycle progression, the regulation of cap-dependent protein translation and through survival signaling by phosphorylation of a pro-apoptotic protein, BAD. Phosphorylation of MYC leads to an increase of MYC protein stability and thereby an increase transcriptional activity.