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E-AB-10614

CCDC99 Polyclonal Antibody

Größe

£106.20

War £118.00

SKU:
E-AB-10614
Zusätzliche Namen:
AA409762,Arsenite related gene 1 protein,Arsenite-related gene 1 protein,CCDC 99,Ccdc99,Coiled coil domain containing 99,Coiled-coil domain-containing protein 99,FLJ20364,FLJ40690,MGC124977,Protein Spindly,Rh,hSpindly,rhabdomyosarcoma antigen MU RMS 40.4A
Anwendung:
WB
Konzentration:
0.2 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse
Buffer:
Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:
Recombinant protein of human SPDL1
Uniprot:
Q96EA4
Synonyme:
arsenite-related gene 1 protein;CCDC99;coiled-coil domain-containing protein 99;protein Spindly;rhabdomyosarcoma antigen MU-RMS-40.4A;rrhabdomyosarcoma antigen protein MU-RMS-40.4A;Spindle apparatus coiled-coil domain-containing protein 1
Weitere Details:
Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment. Interacts with KNTC1 and ZW10. These interactions appear weak and may be transient or indirect.
Versandbedingungen:
Blue Ice