E-AB-10477
MUTYH Polyclonal Antibody

Größe
£106.20
War £118.00
- SKU:
- E-AB-10477
- Zusätzliche Namen:
- A/G specific adenine DNA glycosylase,A/G-specific adenine DNA glycosylase,Adenine DNA glycosylase,CYP2C,E. coli,MGC4416,MUTYH,MYH,MutY,MutY (E. coli) homolog,MutY homolog,MutY homolog (E. coli),Mutyh,hMYH,homolog of,rMYH
- Anwendung:
- IHC, WB
- Konzentration:
- 0.3 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human MUTYH
- Uniprot:
- Q9UIF7
- Synonyme:
- A/G-specific adenine DNA glycosylase;adenine DNA glycosylase;mutY homolog;mutY-like protein;MYH
- Weitere Details:
- This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. Mutations in this gene result in heritable predisposition to colon and stomach cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
- Versandbedingungen:
- Blue Ice