E-AB-10402
ITGB3BP Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-10402
- Zusätzliche Namen:
- Beta 3 endonexin,Beta-3,Beta3 endonexin,Beta3 endonexin long form,CENP R,CENPR,Centromere protein R,HSU37139,Integrin beta 3 binding protein,Integrin beta 3 binding protein (beta3-endonexin),NRIF 3,NRIF3,Nuclear receptor interacting factor,endonexin
- Anwendung:
- IHC
- Konzentration:
- 0.7 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human ITGB3BP
- Uniprot:
- Q13352
- Synonyme:
- beta 3 endonexin;Beta-3-endonexin;beta3-endonexin;CENP-R;CENPR;centromere protein R;HSU37139;integrin beta 3 binding protein (beta3-endonexin);integrin beta-3-binding protein;NRIF3;nuclear receptor-interacting factor 3;TAP20
- Weitere Details:
- This gene encodes a transcriptional coregulator that binds to and enhances the activity of members of the nuclear receptor families, thyroid hormone receptors and retinoid X receptors. This protein also acts as a corepressor of NF-kappaB-dependent signaling. This protein induces apoptosis in breast cancer cells through a caspase 2-mediated signaling pathway. This protein is also a component of the centromere-specific histone H3 variant nucleosome associated complex (CENP-NAC) and may be involved in mitotic progression by recruiting the histone H3 variant CENP-A to the centromere. Alternate splicing results in multiple transcript variants.
- Versandbedingungen:
- Blue Ice