E-AB-10155
COL1A2 Polyclonal Antibody
Größe
£106.20
War £118.00
- SKU:
- E-AB-10155
- Zusätzliche Namen:
- Alpha 2 collagen type I,Alpha 2 type I collagen,Alpha 2 type I procollagen,Alpha 2(I) collagen,Alpha 2(I) procollagen,Alpha-2 type I collagen,CO1A2,COL1A2,Collagen I alpha 2 polypeptide,Collagen alpha 2(I) chain,Collagen alpha-2(I) chain,Collagen of skin
- Anwendung:
- IHC
- Konzentration:
- 0.1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
- Immunogen:
- Recombinant protein of human COL1A2
- Uniprot:
- P08123
- Synonyme:
- alpha 2 type I procollagen;alpha 2(I) procollagen;alpha 2(I)-collagen;alpha-2 type I collagen;collagen alpha-2(I) chain;collagen I, alpha-2 polypeptide;collagen of skin, tendon and bone, alpha-2 chain;collagen, type I, alpha 2;EDSARTH2;EDSCV;epididymis secretory sperm binding protein;OI4;type I procollagen
- Weitere Details:
- This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain.Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon.Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome.Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
- Versandbedingungen:
- Blue Ice