MMP13 Polyclonal Antibody

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£106.20

War £118.00

SKU:: E-AB-10064
Zusätzliche Namen:: CLG 3,CLG3,Collagenase 3,Collagenase3,MANDP1,MMP 13,MMP-13,MMP13,Matrix Metalloproteinase 13,Matrix metallopeptidase 13 (collagenase 3),Matrix metalloproteinase-13,Mmp13
Anwendung:: WB
Konzentration:: 0.4 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: Phosphate buffered solution, pH 7.4, containing 0.05% stabilizer and 50% glycerol.
Immunogen:: Recombinant protein of human MMP13
Uniprot:: P45452
Synonyme:: CLG3;collagenase 3;MANDP1;matrix metalloproteinase 13 (collagenase 3);Matrix metalloproteinase-13;MDST;MMP-13
Weitere Details:: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.