D-AB-10447L
CASP4 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- D-AB-10447L
- Zusätzliche Namen:
- Apoptotic cysteine protease Mih1/TX,CASP-4,CASP4,Caspase 4 apoptosis related cysteine peptidase,Caspase-4 subunit 2,Caspase4,ICE(rel)-II,ICE(rel)II,ICEREL II,ICH2,Mih1/TX,Protease ICH-2,Protease TX,TX
- Anwendung:
- IHC, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Human CASP4 protein expressed by E.coli
- Uniprot:
- P49662
- Synonyme:
- apoptotic cysteine protease Mih1/TX;CASP-4;caspase 4, apoptosis-related cysteine peptidase;caspase 4, apoptosis-related cysteine protease;caspase-4;caspase-4 isoform alpha;ICE and Ced-3 homolog 2;ICE(rel)-II;ICE(rel)II;ICEREL-II;ICH-2;Mih1;Mih1/TX;protease ICH-2;protease TX;TX
- Weitere Details:
- This gene encodes a member of the cysteine proteases that plays important roles in apoptosis,cell migration and the inflammatory response. The encoded protein mediates production of pro-inflammatory cytokines by macrophages upon bacterial infection. Mice lacking the encoded protein are resistant to endotoxic shock induced by lipopolysaccharide. A 5-bp deletion encompassing a splice acceptor junction resulting in alternate splicing and a shorter non-functional isoform in certain mouse strains has been described. Although its official nomenclature is ",caspase 4,apoptosis-related cysteine peptidase", this gene and its encoded protein have historically been called caspase 11. This gene is present in a cluster of three caspase genes on chromosome 9.
- Versandbedingungen:
- Blue Ice