AFP Polyclonal Antibody

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SKU:: D-AB-10223L
Zusätzliche Namen:: AFP,Alpha-fetoglobulin,Alpha-fetoprotein,HPAFP
Anwendung:: IHC
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Human AEP protein expressed by E.coli
Uniprot:: P02771
Synonyme:: AFPD;alpha-1-fetoprotein;alpha-fetoglobulin;alpha-fetoprotein;FETA;HPAFP
Weitere Details:: Alpha-fetoprotein (AFP) is classified as a member of the albuminoid gene superfamily consisting of albumin,AFP,vitamin D (Gc) protein,and alpha-albumin. AFP is a glycoprotein of 591 amino acids and a carbohydrate moiety. AFP is one of the several embryo-specific proteins and is a dominant serum protein as early in human embryonic life as one month,when albumin and transferrin are present in relatively small amounts. It is first synthesized in the human by the yolk sac and liver(1-2 months) and subsequently predominantly in the liver. A small amount of AFP is produced by the GI tract of the human conceptus. It has been proved that AFP may reappear in the serum in elevated amounts in adult life in association with normal restorative processes and with malignant growth. Alpha-fetoprotein (AFP) is a specific marker for hepatocellular carcinoma (HCC),teratoblastomas,and neural tube defect (NTD).