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D-AB-10210L

LDHA Polyclonal Antibody

Größe

£120.60

War £134.00

SKU:
D-AB-10210L
Zusätzliche Namen:
GSD11, L lactate dehydrogenase A chain, LDH M, LDH muscle subunit, LDH1, PIG19 Proliferation-inducing gene 19, l7R2,Cell proliferation-inducing gene 19 protein
Anwendung:
IHC, WB
Konzentration:
1 mg/ml
Aufreinigung:
Affinity Purified
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Host:
Rabbit
Reaktivitäten:
Human, Mouse, Rat
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:
Recombinant Human LDHA protein expressed by E.coli
Uniprot:
P00338
Synonyme:
cell proliferation-inducing gene 19 protein;epididymis secretory sperm binding protein Li 133P;GSD11;HEL-S-133P;L-lactate dehydrogenase A chain;lactate dehydrogenase M;LDH muscle subunit;LDH-A;LDH-M;LDHM;PIG19;proliferation-inducing gene 19;renal carcinoma antigen NY-REN-59
Weitere Details:
LDHA,also named as LDH-M and NY-REN-59,is an enzyme which catalyzes the inter-conversion of pyruvate and L-lactate with concomitant inter-conversion of NADH and NAD+. LDHA is found in most somatic tissues,though predominantly in muscle tissue and tumours,and belongs to the lactate dehydrogenase family. It has long been known that many human cancers have higher LDHA levels compared to normal tissues. It has also been shown that LDHA plays an important role in the development,invasion and metastasis of malignancies. Mutations in LDHA have been linked to exertional myoglobinuria. LDHA has some isoforms with MW 26-40 kDa.
Versandbedingungen:
Blue Ice