LMNA Polyclonal Antibody

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£120.60

War £134.00

SKU:: D-AB-10192L
Zusätzliche Namen:: 70 kDa lamin,CDCD1,CDDC,CMD1A,CMT2B1,Cardiomyopathy dilated 1A (autosomal dominant),EMD2,FPL,FPLD,FPLD2,HGPS,IDC,LDP1,LFP,LGMD1B,LMN 1,LMN A,Lamin,Lamin A,Lamin A/C,Lamin A/C like 1,Lamin C,Lamin-A/C,Limb girdle muscular dystrophy 1B (autosomal dominant)
Anwendung:: WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Human LMNA protein expressed by E.coli
Uniprot:: P02545
Synonyme:: 70 kDa lamin;CDCD1;CDDC;CMD1A;CMT2B1;EMD2;epididymis secretory sperm binding protein;FPL;FPLD;FPLD2;HGPS;IDC;lamin;lamin A/C-like 1;LDP1;LFP;LGMD1B;LMN1;LMNC;LMNL1;MADA;mandibuloacral dysplasia type A;prelamin-A/C;PRO1;renal carcinoma antigen NY-REN-32
Weitere Details:: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants.