CST3 Polyclonal Antibody

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£120.60

War £134.00

SKU:: D-AB-10163L
Zusätzliche Namen:: ARMD11, Amyloid angiopathy and cerebral hemorrhage, CST3 protein, Cystatin 3, CystatinC, Epididymis secretory protein Li 2, Gamma trace, HCCAA, HEL S 2, Neuroendocrine basic polypeptide, Post gamma globulin, bA218C14.4,AD8
Anwendung:: IHC, WB
Konzentration:: 1 mg/ml
Aufreinigung:: Affinity Purified
Lagerbedingungen:: -20[o]C Avoid freeze/thaw cycles.
Hersteller:: Elabscience
Host:: Rabbit
Reaktivitäten:: Human, Mouse, Rat
Buffer:: PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
Immunogen:: Recombinant Human CST3 protein expressed by E.coli
Uniprot:: P01034
Synonyme:: ARMD11;bA218C14.4 (cystatin C);cystatin 3;Cystatin-3;cystatin-C;epididymis secretory protein Li 2;gamma-trace;HEL-S-2;neuroendocrine basic polypeptide;post-gamma-globulin
Weitere Details:: Cystatin C is a 13-kDa inhibitor of cysteine proteinases which is secreted by all cell types and is completely cleared from the organism through glomerular filtration,shown to be an early and sensitive biomarker of renal dysfunction. A mutation in Cystatin C has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions,establishing its role in vascular disease. In addition,this protein has been shown to have an antimicrobial function,inhibiting the replication of herpes simplex virus.