D-AB-10161L
AMPK alpha2 Polyclonal Antibody
Größe
£120.60
War £134.00
- SKU:
- D-AB-10161L
- Zusätzliche Namen:
- 5'-AMP-activated protein kinase catalytic subunit alpha-2,AAPK2,ACACA kinase,AMPK alpha 2 chain,AMPK subunit alpha-2,AMPK2,AMPKa2,AMPKalpha2,Acetyl-CoA carboxylase kinase,HMGCR kinase,Hydroxymethylglutaryl-CoA reductase kinase,PRKAA,PRKAA2,Protein kinase
- Anwendung:
- IHC, WB, IF
- Konzentration:
- 1 mg/ml
- Aufreinigung:
- Affinity Purified
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Host:
- Rabbit
- Reaktivitäten:
- Human, Mouse, Rat
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Immunogen:
- Recombinant Rat Ampk2 protein expressed by E.coli
- Uniprot:
- Q09137
- Synonyme:
- 5'-AMP-activated protein kinase catalytic subunit alpha-2;ACACA kinase;acetyl-CoA carboxylase kinase;AMP-activated protein kinase;Ampk;AMPK alpha-2 chain;AMPK subunit alpha-2;Ampka2;HMGCR kinase;hydroxymethylglutaryl-CoA reductase kinase;protein kinase, AMP-activated, alpha 2 catalytic subunit
- Weitere Details:
- The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- Versandbedingungen:
- Blue Ice